Mesothelium is the protective tissue that covers the chest hollow space, abdominal hollow space and the hollow space around the heart and also produces a special lubricating fluid that allows the internal organs of the body to go around. Malignant Mesothelioma can be defined as the cancer of the mesothelial cells which be converted into abnormal and start dividing without any peacefulness. Majority of the mesothelioma patients have a prior history of exposure to asbestos.
Of these, Epithelioid is the most ordinary (50% to 70% cases) and stands the best chance of recovery. Sarcomatoid type is seen in 7% to 20% cases whereas mixed/biphasic type is seen in 20% to 35% cases. Approximately, ?of the total cases of Mesothelioma originates in the chest hollow space (pleura) and is known as pleural mesothelioma. The cancer affecting the lining of the abdomen (peritoneum) is called the peritoneal mesothelioma and that affecting the tac like space around the heart (pericardial hollow space) is called the pericardial mesothelioma. Mesothelioma at times also affects the covering layer of the testicles. But, the last two types of cases are quite rare. The tumors of the mesothelium can either be benign (non cancerous) or malignant (cancerous). So whenever there are symptoms like tininess of breath, pain in chest/abdomen or swelling in the abdomen, you should consult your doctor immediately. With the initial X-rays and scans, the doctor may look inside the chest hollow space (in case of pleural tumor) with an instrument called thoracoscope and the test is called thoracoscopy. In case of tumor in peritoneum the doctor may go for peritoneoscopy with the help of a tool called peritoneoscope. Irrevocably, if the abnormal tissue is found then a biopsy is done, whereby a piece of the unnatural tissue is cut out and placed under microscope for examination.
With the confirmed diagnosis of Mesothelioma it is also essential to learn its stages i.e. whether it is in localized stage or in advanced stage. In the localized stage, the cancer is found in the lining of the chest hollow space or in the diaphragm or the lung. Advanced malignant Mesothelioma can over again be divided into 3 stages namely stage II, III and IV. In stage II, the cancer spreads beyond the chest lining to lymph nodes and in stage III it spreads into chest wall, center of the chest, heart, through the diaphragm or abdominal lining, etc. The final or the fourth stage is the one in which the cancer has already spread to distant organs.
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